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New methods reveal cancer mechanism in ancient genes
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies
Switching sides: How MLL-rearranged leukemias leverage oncoproteins to evade treatment
From the Henikoff Lab, Basic Sciences Division
An old drug gets a new look: DNA damaging agent aclarubicin found to disrupt chromatin and stimulate RNA Pol II elongation
From the Henikoff Lab, Basic Sciences Division and Cancer Basic Biology Program of the Cancer Consortium
Classifying prostate cancer subtypes from liquid biopsies
From the Ha and Nelson labs, Human Biology Division
MulTI-Tag: your ticket to profiling chromatin
From the Henikoff Lab, Cancer Basic Biology Program, Cancer Consortium.
License to Kill: Latency HIV-CRISPR pinpoints how to blow latent HIV’s cover
From the Emerman and Henikoff Labs, Pathogen Associated Malignancies and Cancer Basic Biology Programs, Cancer Consortium.
Peeling back the layers of a cell’s epigenomic data
From the Henikoff and Setty labs, Basic Sciences and Public Health Sciences Divisions
Epigenetic heterogeneity helps cancer cells change their minds
From the Henikoff Lab, Basic Sciences Division and the Meshinchi Lab, Clinical Research Division
You’ve got something in your eye: cellular reprogramming in development and cancer
From the Henikoff Lab, Basic Sciences Division
Short H2A histones, part II: a natural-born oncogene lurking in our genomes
From the Malik, Henikoff, Bleakley, and Bradley labs, Basic Sciences Division
Short H2A histones, part I: parental conflict at the evolutionary scale
From the Malik and Henikoff labs, Basic Sciences Division
The inner workings of a pioneer factor
From the Henikoff lab, Basic Sciences Division
CUT&Tag for the win
From the Henikoff lab, Basic Sciences Division
Actin-related proteins rule in nucleosome remodeling
From Dr. Sandipan Brahma, in the Henikoff lab, Basic Sciences Division
Keeping up with CUT&RUN
From the Henikoff lab, Basic Sciences Division
Dr. Jay Sarthy receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award
He will use the funding to study brain tumors in children
A salt bath and a haircut clean up centromeric chromatin
From the Henikoff Lab, Basic Sciences Division
The same but different: reconciling the diversity of centromeres with their highly conserved function
From the Henikoff Lab, Basic Sciences Division
Good News: Henikoff Lab celebrates 35 years; Hutch writer earns journalism award; Pat Heath wins coveted Wyckoff award; Hutch vanity plate signatures at 2,300
Celebrating faculty and staff achievements