CSRN Coordinating and Communications Center

The Cancer Screening Research Network (CSRN) Coordinating and Communications Center (CCC) is led by three senior principal investigators at Fred Hutch Cancer Center who bring complementary training and expertise encompassing all scientific and functional aspects critical to the CSRN mission. The CCC will develop study protocols and train and monitor the nine U.S. organizations that recruit participants to studies. Other investigators will provide additional expertise in recruitment and retention of minority and underserved populations, cancer diagnostic pathways and clinical practice more generally. 

CCC Leadership

Garnet Anderson, PhD

Garnet Anderson, PhD

Co-Principal Investigator, CCC, Fred Hutch
Senior Vice President and Director, Public Health Sciences Division, Fred Hutch
Fred Hutch 40th Anniversary Endowed Chair, Fred Hutch
Ruth Etzioni, PhD

Ruth Etzioni, PhD

Co-Principal Investigator, CCC, Fred Hutch
Professor, Cancer Prevention Program, Public Health Sciences Division, Fred Hutch
Member, Translational Data Science Integrated Research Center, Fred Hutch
Rosalie and Harold Rea Brown Endowed Chair, Fred Hutch
Scott Ramsey, MD, PhD

Scott Ramsey, MD, PhD

Co-Principal Investigator, CCC, Fred Hutch
Director, Hutchinson Institute for Cancer Outcomes Research (HICOR), Fred Hutch
Member, Translational Data Science Integrated Research Center, Fred Hutch

The CCC is Organized Into Four Units

Modeling and Evaluation Unit (MEU)

MEU provides expertise and guidance on multi-cancer detection test selection and critical trial design features through review of current literature and data relevant to screening for the targeted cancers, microsimulation modeling examining critical screening performance metrics, population level rates and our (limited) understanding of the natural history of cancer. Dr. Etzioni provides oversight of this unit.

Communications Unit (CommsU)

CommsU develops communications strategies and approaches and facilitates tailoring of study messages to the internal and external audiences. This unit maintains websites, social media feeds and participant messaging related to recruitment, trial participation and retention. The CommsU will also create a community advisory board of stakeholders to seek broader engagement in the design, implementation, and use of MCD testing in real-world settings. Dr. Ramsey provides oversight of this unit.

Clinical Unit (ClinU)

ClinU will provide training coordination, support, monitoring and quality assurance of ACCESS site operations, specimen testing and biorepository functions. They will also be responsible for centralized medical record review and coding of clinical outcomes, including medical record abstractions regarding MCD testing, potential adverse events, diagnostic procedures and results, and potential adverse effects. Dr. Anderson provides oversight of this unit.

Administration Unit (AdminU)

AdminU provides logistical support for all CSRN committees, working groups and national meetings. This unit develops and maintains all official study documents and central Institutional Review Board approvals, and develops and maintains all necessary affiliation and data use agreements. Drs. Anderson and Ramsey provide oversight of this unit.

CCC Co-Investigators

Charles Drescher, MD

Charles Drescher, MD

Affiliate Investigator, Translational Outcomes Research, Public Health Sciences, Fred Hutch
Rachel Issaka, MD, MAS

Rachel Issaka, MD, MAS

Associate Professor, Public Health Sciences, Fred Hutch
Associate Professor, Gastroenterology and Hepatology, Clinical Research Division, Fred Hutch
Associate Professor, Hutchinson Institute for Cancer Outcomes Research (HICOR), Fred Hutch
Kathryn Surace-Smith Endowed Chair in Health Equity Research, Fred Hutch
Vida Henderson, PhD, PharmD

Vida Henderson, PhD, PharmD

Assistant Professor, Cancer Prevention Program, Public Health Sciences Division, Fred Hutch
Affiliate Assistant Professor, Department of Health Systems and Population Health University of Washington
Paul Lampe, PhD

Paul Lampe, PhD

Head, Translational Research Program, Fred Hutch
Professor, Public Health Sciences Division, Fred Hutch
Professor, Human Biology Division, Fred Hutch
Christoph Lee, MD, MS, MBA

Christoph Lee, MD, MS, MBA

Physician, Radiology, Fred Hutch
Professor, Department of Radiology, University of Washington School of Medicine
Viswam S. Nair, MD, MS

Viswam S. Nair, MD, MS

Associate Professor, Clinical Research Division, Fred Hutch
Medical Director, Lung Cancer Early Detection and Prevention Clinic, Fred Hutch
Attending Physician, Fred Hutchinson Cancer Center/UW Medical Center - Montlake
Matthew Triplette MD, MPH

Matthew Triplette MD, MPH

Associate Professor, Public Health Sciences Division, Fred Hutch
Associate Professor, Clinical Research Division, Fred Hutch
Medical Director, Lung Cancer Screening, Fred Hutch
Medical Director, Living Tobacco-Free Services, Fred Hutch

Frequently Asked Questions

CSRN is the first large scale network to focus on cancer screening. It will be led by clinicians who perform cancer screening as part of their routine practice. CSRN will engage providers who work with various populations receiving routine healthcare in a variety of healthcare settings.

The first effort for CSRN is a pilot study called the Vanguard study which will inform the design of future large trials to evaluate MCD assays.

Yes. The CSRN plans to investigate a variety of emerging technologies for cancer screening. These may include screening methods that involve imaging, biomarkers, procedures, combinations of the above, or tests that have not yet been invented.

Because CSRN is funded through a cooperative agreement, NCI plays a role in all aspects of the CSRN. Read more on the NCI CSRN site.

CCC Administrative Team

Ari Bell-Brown

Collaborative Science Manager

Nahom Daniel

Project Coordinator

Karma Kreizenbeck

Communications Project Director

Allison Matson

Research Administrator

Long P. Nguyen

Administrative Coordinator

Jenny Schoenberg

IRB/Regulatory

Kate Watabayashi

Senior Program Manager

Emily Wion

Director, Research Outcomes and Clinical Field Center Operations

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