Collaborating to understand how HIV spreads among vulnerable people
Overbaugh studies HIV transmission in vulnerable people, including commercial sex workers and infants born to mothers with HIV. In the 1990s, before the advent and widespread availability of antiretroviral drugs, she was part of the joint Kenya-U.S. team that demonstrated that HIV could be transmitted through breast milk. For over 25 years, she’s participated in a rich collaboration with Kenyan and University of Washington scientists to foster a longstanding cohort of commercial sex workers who generously help researchers better understand HIV risk and transmission.
Overbaugh’s work also highlighted how factors like injectable hormonal contraceptives and certain sexually transmitted infections can influence risk of HIV infection and revealed aspects of maternal anti-HIV immunity that reduce transmission from mother to child. Her research in infants could help inform HIV vaccine design by showing how potent immune proteins that protect against HIV infection, called neutralizing antibodies, can be created quickly after infection.
Advancing the public good
The mission of the Academy is not merely to recognize outstanding individuals, but to advance the public good. Overbaugh, who holds the Endowed Chair for Graduate Education at the Hutch, shares these values. She is as renowned for her efforts in graduate mentorship and training as she is for her world-class science. Issues of equity and diversity in science are particular areas of interest, she said.
As one of this year’s 276 new members, Overbaugh joins a class that includes many impressive women, such as lawyer, academic and activist Anita Hill; and singer, songwriter and activist Joan Baez. She is the 12th Hutch faculty member elected to the Academy and the latest in a spate of outstanding women researchers from the Hutch to be elected.
When Fred Hutch HPV researcher Dr. Denise Galloway was elected last year, Overbaugh loaned her a scarf for the membership ceremony.
“I think it gave me good karma,” she said.