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When scientific hypotheses don’t pan out
Research studies are often built around an educated guess. What happens when those guesses are wrong?

Vitamin E, selenium linked to increased prostate cancer risk
New Fred Hutch study raises caution about high doses of supplements

SELECT data shows vitamin E increases prostate cancer risk
Trial analysis by PHS investigators reveals supplement hazard in largest-ever prostate cancer prevention study

Enduring effects of lung-cancer supplement study
Six years after CARET study ended, women who took supplements remained at higher risk for lung cancer, death