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Engineered HSV can trigger genetic chain reaction, rejigger HSV genes during co-infection
Proof-of-concept work raises hope that ‘gene drive’ could one day form basis of curative gene therapy for herpes
Herpes cure with gene editing makes progress in laboratory studies
Fred Hutch virologists eliminated at least 90% of HSV-1 in preclinical models of oral and genital herpes and reduced viral shedding in a study published in Nature Communications
Sleuthing the immune system’s mysterious T-regs
Dr. Jennifer Lund probes why regulatory T cells show up when trouble comes around
Scientists predict progress against COVID-19, cancer in 2021
After a challenging and deadly 2020, some hopeful predictions for the new year
A year of research dominated by the coronavirus
Scientists applied diverse expertise to pandemic in 2020 while advancing discoveries and cures for cancer
Tip Sheet: Colorectal cancer, COVID-19 super-spreading, gene therapy for herpes, contagious cancer in Tasmanian devils – and more
Summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.
A cure for herpes? There is progress to report
Mouse studies show gene therapy can cause big drop in latent infections
¿La cura del herpes? Hay avances que reportar
Los estudios con ratones muestran que la terapia génica puede reducir muchísimo las infecciones inactivas
Antibody blocks Epstein-Barr virus in preclinical trial
Hutch-discovered protein blocks virus linked to cancers, mono, autoimmune diseases
Correlation is not (necessarily) causation
Or, how we know herpes doesn’t cause cervical cancer — and HPV does
Rethinking an old viral foe
Why does a common virus plague bone marrow transplant patients? New study challenges dogma, opens door to new therapies.
Dr. Joshua Hill receives Amy Strelzer Manasevit grant award
Award will help fund ‘paradigm shift’ in diagnosing post-transplant infections
When scientific hypotheses don’t pan out
Research studies are often built around an educated guess. What happens when those guesses are wrong?
Stealing a secret from an unwelcome virus
An unexpected discovery in a herpes lab might bring relief to cancer patients
Experimental herpes drug pritelivir more effective than standard treatment
Pritelivir reduces viral shedding and lesions better than valacyclovir, study shows
Can gene editing cure herpes?
Fred Hutch study shows ‘pathway to potential cure’ for herpes simplex and other latent viruses
Fred Hutch medical tipsheet for July
Cancer moonshot, research, global health, HIV vaccine, health care policy story ideas and more