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Polycomb repressor proteins get trapped in a web of HSATII DNA upon DUX4 activation, leading to DNA damage
From the Tapscott Lab, Human Biology Division

Novel protein FLIP protects cells against DNA damage and ensures cell viability after replication stress
From the Adeyemi Lab, Basic Sciences Division

Swing and a hit! RecB contacts RecC to repair DNA breaks
From the Smith Lab, Basic Sciences Division

Taking a closer look at DNA double-strand break hotspots
From the Smith Lab, Basic Sciences Division

LinE proteins lead the way in DNA break hotspot determination
From the Smith Lab, Basic Sciences Division

Genomic attributes predict cancer treatment responsiveness
From the Nelson Lab, Human Biology & Clinical Research Divisions

Alter ego: RNA helicase is recruited to sites of DNA damage
From the Warren Lab, Clinical Research Division

One more hat: new roles for TGFβ in the DNA damage response
From the Paulovich Lab, Clinical Research Division, and colleagues

Taking the long way ‘round: the circuitous molecular route to DNA repair
From the Smith Lab, Basic Sciences Division

Two early-career Fred Hutch scientists receive prestigious fellowships for prostate cancer research
Alexandra Corella wins Ford Foundation funding; Sander Frank earns NIH training fellowship

Testing for inherited mutations could benefit men with advanced prostate cancer
Familial errors in DNA-repair genes are unexpectedly common in men with metastatic prostate cancer, and could help guide therapy and inform cancer screening in family members

Fred Hutch researcher Gerald Smith named a fellow of the American Academy of Microbiology
Smith joins 78 others in the prestigious academy this year that recognizes people who have made significant contributions in the field of microbiology

Smith antibiotics study wins Gates grant
The $100,000 one-year grant will fund the development of a new class of antimicrobial drugs to treat TB and limit the evolution of resistance to antibiotics