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New methods reveal cancer mechanism in ancient genes
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies
Polycomb repressor proteins get trapped in a web of HSATII DNA upon DUX4 activation, leading to DNA damage
From the Tapscott Lab, Human Biology Division
Mellon, a single-cell analysis tool, identifies transitory cells and differentiation mechanisms
From the Setty Lab, Basic Sciences Division
Maxspin: a sensitive, quantitative method for identifying spatially varying genes
From the Newell Lab, Virology and Infectious Disease Division
Dr. Sita Kugel receives V Foundation Translational Research Award
Grant makes possible a clinical trial of targeted treatment for pancreatic cancer
A seesaw between transcription and translation restrains bladder carcinogenesis
From the Hsieh Lab, Human Biology Division
Cbf1 hace las veces de policía de tránsito transcripcional para equilibrar la función del centrómero
Del laboratorio Biggins, División de Ciencias Básicas
Cbf1 plays transcriptional traffic cop to balance centromere function
From the Biggins lab, Basic Sciences Division
New therapeutic strategy turns a cancer’s advantage into its downfall
In the lab, researchers use synthetic mRNA to trick tumors into manufacturing cancer-specific poison
Dr. Steven Hahn elected to American Academy of Microbiology
Revealed fundamental properties of molecular machinery that creates mRNA
Overlooked stretches of DNA could hide cancer-causing mutations
New cutting-edge technique sheds light on difficult-to-study DNA regions, potential drug targets
How a common cancer mutation actually drives cancer — and how to correct it
High-tech approach solves ‘real mystery’ in many cancers