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New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
March 26, 2025
New methods reveal cancer mechanism in ancient genes
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies
More to brain tumors than meets the eye
Fred Hutch researchers find new way to classify tumors based on their underlying biology rather than how they look
Benign meningiomas can’t stop YAP-ing, but aggressive subtypes are more soft-spoken
From the Holland Lab, Human Biology Division
Fred Hutch launches rare cancer research effort
New TRACER initiative aims to accelerate advances through multidisciplinary collaboration and innovative approaches
Risky business: Understanding how numbers, percentages and data impact cancer care
Statistics can simultaneously enlighten and confuse patients
New technique could help make precision medicine more widely available
Simple CUT&Tag adaptation gives information about genetic regulatory elements in formalin-fixed tumor samples
Brain cancer expert Dr. Eric Holland receives Endowed Chair in Cancer Biology
Chair recognizes comprehensive vision, contributions to solid tumor research
Introducing the Brain-UMAP: a reference map of the human brain
From the Holland lab, Human Biology Division
Melding data creates wider landscape of brain cancer
New computational visualization tool allows researchers to compare different tumor types, normal brain tissue, pinpoint cancer-promoting alterations
Oncogenic role of a developmentally regulated NTRK2 splice variant
From the Holland Lab, Human Biology Division
Innovative Holland Lab mouse model helps tease apart YAP1’s role in brain cancer
From the Holland Lab, Cancer Basic Biology Program, Cancer Consortium.
Transformative $78M gift to establish new precision oncology institute
Gift will accelerate center’s leadership in the future of cancer research
Holland receives NCI Outstanding Investigator Award
Neuroscientist will tackle genetic abnormalities that drive cancers and could be therapeutic targets
New strategy to weather the (cytokine) storm
From the Gujral Lab, Human Biology Division
Using AI to identify potential COVID-19, cancer therapies
Early findings show current drugs might be repurposed to calm COVID-19’s cytokine storms, treat metastatic prostate cancer
YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets
From the Holland, Paddison, Vasioukhin, and Gujral labs, Human Biology Division
The NTRK2 splice variant TrkB.T1 plays a vital role in human glioma
From the Holland lab, Human Biology Division
New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs
This gene is fused to many partner genes in different tumors. Now, scientists know it causes cancer — and how they might intervene