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New methods reveal cancer mechanism in ancient genes
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies

More to brain tumors than meets the eye
Fred Hutch researchers find new way to classify tumors based on their underlying biology rather than how they look

Fred Hutch launches rare cancer research effort
New TRACER initiative aims to accelerate advances through multidisciplinary collaboration and innovative approaches

Risky business: Understanding how numbers, percentages and data impact cancer care
Statistics can simultaneously enlighten and confuse patients

New technique could help make precision medicine more widely available
Simple CUT&Tag adaptation gives information about genetic regulatory elements in formalin-fixed tumor samples

Brain cancer expert Dr. Eric Holland receives Endowed Chair in Cancer Biology
Chair recognizes comprehensive vision, contributions to solid tumor research

Introducing the Brain-UMAP: a reference map of the human brain
From the Holland lab, Human Biology Division

Melding data creates wider landscape of brain cancer
New computational visualization tool allows researchers to compare different tumor types, normal brain tissue, pinpoint cancer-promoting alterations

Oncogenic role of a developmentally regulated NTRK2 splice variant
From the Holland Lab, Human Biology Division

Transformative $78M gift to establish new precision oncology institute
Gift will accelerate center’s leadership in the future of cancer research

Holland receives NCI Outstanding Investigator Award
Neuroscientist will tackle genetic abnormalities that drive cancers and could be therapeutic targets

New strategy to weather the (cytokine) storm
From the Gujral Lab, Human Biology Division

Using AI to identify potential COVID-19, cancer therapies
Early findings show current drugs might be repurposed to calm COVID-19’s cytokine storms, treat metastatic prostate cancer

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets
From the Holland, Paddison, Vasioukhin, and Gujral labs, Human Biology Division

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs
This gene is fused to many partner genes in different tumors. Now, scientists know it causes cancer — and how they might intervene

Fred Hutch–led team receives $6M to study deadly brain tumor
Researchers seek deeper understanding of ependymoma biology to aid treatment discovery

Bringing personalized oncology to cancer prediction — and prevention
Unique $2.4M NCI-NIEHS award teams Hutch cancer geneticists, epidemiologists and oncologists to use mutation rate to predict individual cancer risk

Brain cancer subtype caused by single gene fusion
Hutch researchers create genetically relevant model to examine the biology of supratentorial ependymomas