Hutch News

New methods reveal cancer mechanism in ancient genes

New methods reveal cancer mechanism in ancient genes

Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies
Hutch NewsMarch 03, 2025
New technique could help make precision medicine more widely available

New technique could help make precision medicine more widely available

Simple CUT&Tag adaptation gives information about genetic regulatory elements in formalin-fixed tumor samples
Hutch NewsOctober 04, 2023
Melding data creates wider landscape of brain cancer

Melding data creates wider landscape of brain cancer

New computational visualization tool allows researchers to compare different tumor types, normal brain tissue, pinpoint cancer-promoting alterations
Hutch NewsApril 10, 2023
Holland receives NCI Outstanding Investigator Award

Holland receives NCI Outstanding Investigator Award

Neuroscientist will tackle genetic abnormalities that drive cancers and could be therapeutic targets
Hutch NewsOctober 29, 2021
Using AI to identify potential COVID-19, cancer therapies

Using AI to identify potential COVID-19, cancer therapies

Early findings show current drugs might be repurposed to calm COVID-19’s cytokine storms, treat metastatic prostate cancer
Hutch NewsSeptember 30, 2021
YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets

YAP1 gene fusions are oncogenic drivers in several tumor types and potential therapeutic targets

From the Holland, Paddison, Vasioukhin, and Gujral labs, Human Biology Division
Science SpotlightSeptember 21, 2020
New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs

New study shows cancer-causing ‘Frankengene’ mutation could be target for new drugs

This gene is fused to many partner genes in different tumors. Now, scientists know it causes cancer — and how they might intervene
Hutch NewsJuly 16, 2020
Brain cancer subtype caused by single gene fusion

Brain cancer subtype caused by single gene fusion

Hutch researchers create genetically relevant model to examine the biology of supratentorial ependymomas
Hutch NewsJune 26, 2018