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Mutant’s partner in crime could be target for future cancer therapy
Fred Hutch scientists discover a new player — and possible drug target — in a critical biological process that’s skewed in tumors with certain mutations
Stress, caused by RNA:DNA hybrids, holds the key to treating select leukemias
From the Stanley Lee lab, Translational Science and Therapeutics Division
Circling back to RNA sequencing data to map recursive splice sites
From the Robert Bradley Lab, Public Health Sciences and Basic Sciences Divisions & Cancer Consortium
Mutant KRAS signaling drives alternative splicing in lung cancer cells
From the Berger Lab, Human Biology Division
Year in Pictures: 2022
A look back at the year through compelling images
Oncogenic role of a developmentally regulated NTRK2 splice variant
From the Holland Lab, Human Biology Division
New therapeutic strategy turns a cancer’s advantage into its downfall
In the lab, researchers use synthetic mRNA to trick tumors into manufacturing cancer-specific poison
Holland receives NCI Outstanding Investigator Award
Neuroscientist will tackle genetic abnormalities that drive cancers and could be therapeutic targets
How RNA-altering drugs might improve anticancer immunotherapies
In lab study, brief disruptions of gene machinery make tumor cells more 'visible' to immune system
Omics made easier
To see the big picture, just add ‘ome’
Your vote needed! Hutch science competes in 'STAT Madness'
Studies by Drs. Justin Taylor, Robert Bradley are finalists in annual competition for best biomedical advance
CRISPR-based tool solves genetic mystery 80 million years in the making
Certain DNA sequences haven’t evolved since humans and mice diverged. But why?
How a common cancer mutation actually drives cancer — and how to correct it
High-tech approach solves ‘real mystery’ in many cancers
Finding branchpoint needles in a haystack of sequencing data
From the Bradley Lab, Basic Sciences & Public Health Sciences Divisions
Investing in the future: 5 researchers benefit from President’s Young Investigator Awards
Five researchers get surprise grants through new President’s Young Investigator Awards
Biologist Bradley joins Center
Robert Bradley brings expertise in understanding alternative splicing to Basic Sciences and Public Health Sciences divisions