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Insulin resistance turns tidy brain cells into slobs — which could be a link between diet and neurodegenerative diseases
New work in fruit flies shows that a high-sugar diet impairs “housekeeping” brain cells

Finding the ‘sweet spot’: what hungry flies can teach us about human metabolism
From the Rajan Lab, Basic Sciences Division

You’ve got something in your eye: cellular reprogramming in development and cancer
From the Henikoff Lab, Basic Sciences Division

Oncohistones: A Vicious Cycle
From the Henikoff lab, Basic Science Division, and the Olson lab, Clinical Research Division

Pavarotti’s (actin) debut
From the Parkhurst lab, Basic Sciences Division

Centromeric proteins find their own niche
From the Malik Lab, Basic Sciences Division

(Wash)ing the nuclear envelope
From the Parkhurst lab, Basic Sciences Division.

Ways to improve body image in Drosophila
From the Rajan lab, Basic Sciences Division

Actin gone wild
From the Malik lab, Basic Sciences Division

Fruit fly study IDs missing links in fat-signaling system
Hormone alerts brain to fat-storage status, but its packaging system goes awry in obesity

The sixth samurai: Finding a gene that divides one species from another
How six male flies — among more than 300,000 females — led to the discovery of an evolution-driving gene

Q&A: How evolutionary biologists got lucky with a sperm discovery
Drs. Harmit Malik and Mia Levine on a male fruit fly protein necessary for embryo survival

Study reveals how cells’ nuclei keep their shape
Scientists discover a protein that keeps cellular nuclei from shriveling, a hallmark of old age and the premature-aging disease progeria

Discovery in fruit flies may provide insights into some poor prognosis leukemias
Finding from the Fred Hutchinson Cancer Research Center’s Basic Sciences Division newly identifies key protein function, potential therapeutic target

Genetic Discovery in Fruit Flies May Open New Avenues for Understanding Cancer Growth in Humans
Finding also offers better testing ground for anti-cancer drugs