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Oral Shedding: A Kaposi Sarcoma Mystery
From the Schiffer Lab, Vaccine and Infectious Disease Division and Clinical Research Division
Driver’s ed: watching HSV co-infection and recombination in vivo
From the Jerome Lab, Vaccine & Infectious Disease Division
Laying the groundwork for a new cancer-preventive vaccine
Fred Hutch scientists garner large NCI award to uncover secrets of immune response to virus behind Kaposi sarcoma
Engineered HSV can trigger genetic chain reaction, rejigger HSV genes during co-infection
Proof-of-concept work raises hope that ‘gene drive’ could one day form basis of curative gene therapy for herpes
Herpes cure with gene editing makes progress in laboratory studies
Fred Hutch virologists eliminated at least 90% of HSV-1 in preclinical models of oral and genital herpes and reduced viral shedding in a study published in Nature Communications
Exit or not? HSV-1 infection redistributes heterochromatin to exit the nucleus
From the Avgousti lab, Human Biology Division
Dr. Larry Corey receives Alexander Fleming Award
Virologist honored by peers for his lifetime achievements against infectious diseases
Researching herpes treatments with 'skin-on-chip' technology
Experimental device grows human skin, infects and treats it; could advance disease modeling in labs
Researchers refine experimental gene therapy for herpes
Treatment sharply reduced viral shedding in laboratory mice
Sequence diversity in cancer-causing viruses
From the Mullins lab, University of Washington and the Vaccine and Infectious Disease Division
A year of research dominated by the coronavirus
Scientists applied diverse expertise to pandemic in 2020 while advancing discoveries and cures for cancer
A cure for herpes? There is progress to report
Mouse studies show gene therapy can cause big drop in latent infections
New gene therapy approach eliminates at least 90% latent herpes simplex virus 1
In Nature Communications, Fred Hutch scientists demonstrate in a mouse model how gene therapy could cure an infection that afflicts billions of people
Fred Hutch scientists identify new nerve growth factor
A surprising discovery in a herpes lab points to new treatments for nerve damage