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Towards accessible gene therapy: in vivo base editing to cure Sickle Cell Disease
From the Cancer Consortium Lieber Lab, Department of Laboratory Medicine and Pathology, University of Washington

Engineered HSV can trigger genetic chain reaction, rejigger HSV genes during co-infection
Proof-of-concept work raises hope that ‘gene drive’ could one day form basis of curative gene therapy for herpes

Iniciativa para llevar la genoterapia a países de bajos ingresos
Del Laboratorio Adair, División de Ciencias Traslacionales y Terapéuticas

Advocating for bringing gene therapy to low-income countries
From the Adair Lab, Translational Science and Therapeutics Division

A foamy way to improve cost, efficiency and safety of gene therapy
From the Stephan Lab, Translational Science and Therapeutics Division

Taking a frothy risk to advance gene therapy
Fred Hutch scientists hope foam could be a cost-reducing, access-enhancing vehicle for delivering future gene therapies

Could a medicated foam make gene therapies more accessible?
In Nature Communications, Fred Hutch bioengineer Matthias Stephan, MD, PhD, reports latest effort to use innovative materials to improve immune-based therapies.

‘If you want to go far, go together’
Fred Hutch scientist Dr. Jennifer Adair partners with colleagues around the globe to make gene therapies more effective and more widely available

Dr. Hans-Peter Kiem awarded amfAR grant for research on HIV gene therapy
Potential cure builds on unexpected findings about hematopoietic stem cells

Liver-humanized mice to study hepatis B virus infection
From the Jerome lab, Vaccine and Infectious Disease Division

Fred Hutch hosts inaugural Dr. E. Donnall Thomas Symposium
Event draws leading researchers in transplantation, gene and cell therapy

Sifting through the haystack: Optimizing hematopoietic stem cell purification for gene therapy
From the Kiem Lab, Clinical Research Division

Timothy Ray Brown, who inspired millions living with HIV, dies of leukemia
For more than a decade after a stem cell transplant, he was the only person known to be cured of HIV/AIDS

Tip Sheet: Colorectal cancer, COVID-19 super-spreading, gene therapy for herpes, contagious cancer in Tasmanian devils – and more
Summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.

A cure for herpes? There is progress to report
Mouse studies show gene therapy can cause big drop in latent infections

DNA barcoding allows tracking of clonal dynamics after gene therapy
From the Adair and Kiem Groups, Clinical Research Division

$3.5M grant to develop safer treatment for inherited blood disorders
Scientists will study radioactive particles that can precisely deliver a potent punch

The present and future of science intersect in Seattle
Highlights from the annual meeting of the American Association for the Advancement of Science

Future of medicine: Body heal thyself
Panel of Hutch scientists talked gene therapy, big data and financial toxicity to reporters at annual AAAS meeting