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A quarter century of lifesaving discoveries in prostate cancer
Pacific Northwest Prostate Cancer SPORE insights have transformed patient care and understanding of prostate cancer biology, supported drug discovery worldwide

Detecting, detecting! A qPCR assay to detect WPRE sequences in CAR-T and TCR-T cells
From the Yeung lab, Translational Science and Therapeutics and Clinical Research Division

Extending efficacy for CAR T-cell therapies
Dr. Shivani Srivastava receives NCI MERIT Award to investigate how to improve engineered cancer immunotherapies against solid tumors through reservoirs of self-renewing immune cells

Dr. Phil Greenberg becomes president-elect of American Association for Cancer Research
Immunologist looks ahead to international leadership role

Send in the CARs: mesothelin-targeted CAR T cells against AML
From the Meshinchi Lab, Clinical Research Division, and Cancer Consortium colleagues

Investment in business development pays dividends for research, patients
Fred Hutch tech transfer specialists help scientists navigate path to bringing innovations to patients

Remodeling the tumor microenvironment for improved CAR T-cell therapy
From the Riddell and Srivastava Labs, Clinical Research Division

If at first you don’t succeed: Testing outcomes of second CAR T-cell infusions
From the Turtle group and collaborators, Clinical Research Division

Rewiring T cell death signaling enhances T cell function and persistence
From the Greenberg lab, Clinical Research Division

Antiviral immunity survives CD19-directed therapy
From the Hill and Turtle laboratories, Vaccine and Infections Disease Division and Clinical Research Division

Immunotherapy prevents relapse in small leukemia trial
Engineered T cells kept leukemia from returning in 12 high-risk patients

“Exciting” but early results in trial of immunotherapy for myeloma
Cancer cells disappeared rapidly in patients with high-risk, treatment-resistant disease

Immunotherapy strategy for ovarian cancer aims to rewire a ‘kill switch’ to ramp-up signal
T cells bearing a new engineered protein boost immunotherapy’s effectiveness in laboratory models of AML, ovarian, pancreatic cancers

First systematic study of infections after CAR T-cell therapy
“Benchmark” research could help reduce complications of emerging immunotherapy

Forum at Fred Hutch focuses on the hottest developments in cancer immunotherapy
Immune-based treatments move from the fringes to the spotlight

5 researchers receive awards to explore immunotherapy single-cell RNA sequencing
Projects accelerate Hutch position as early adopter of scRNA-seq technology

A Q&A with immunotherapy researcher Dr. Rachel Perret
As part of a world-class immunotherapy research team, Perret is working her ‘dream job’ — trying to bring T-cell therapy to all who need it

6 questions in cancer immunotherapy
From cancer vaccines to engineered T cells, experts weigh in on the big unknowns

NCI awards $11.5 million to Fred Hutchinson Cancer Research Center to lead breast cancer research consortium
Projects include developing targeted therapies to treat drug-resistant tumors