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CAR-T cells and checkpoint inhibitors: ripping out the breaks, or hitting the turbo?
From the Turtle Lab, Clinical Research Division

Cancer care: From ‘sledgehammer’ to precision cellular therapy
AACR progress report: new immunotherapies improve outcomes, but access to care and clinical trials for many still lags

Fred Hutch mourns sudden loss of Dr. Martin ‘Mac’ Cheever
A long career devoted to bringing immunotherapies from bench to bedside

How RNA-altering drugs might improve anticancer immunotherapies
In lab study, brief disruptions of gene machinery make tumor cells more 'visible' to immune system

Repair of key immune organ triggered by change in how immune cells die
Scientists learn how dying T cells promote regrowth of thymus

New regional collaborations will accelerate innovation in data-intensive medical science
Three research teams in Washington, Oregon and British Columbia receive pilot funding from Cascadia Data Alliance

Immunotherapy trial in advanced bladder and other urinary tract cancers shows 'exciting' results
'Practice-changing' data shows patients with advanced urothelial carcinoma survive longer with immune-boosting drug after chemo

Study links common immune cell to failure of checkpoint inhibitors in lung cancer
New research suggests how to better predict which patients will respond to immunotherapy

New program to fast-track lung cancer research from lab to clinic
Patient-focused science at the heart of $13M National Cancer Institute grant

Cancer cells reconnect with their inner child to evade immunotherapy
Turning on an embryonic gene may help some tumors resist immune checkpoint inhibitors

The latest in prostate cancer research: 7 takeaways
7 takeaways from community symposium highlighting recent advances in prevention, screening and treatment

Dr. Cameron Howard Lee named 2019 Helen Hay Whitney Fellow
Biggins Lab postdoc will look at relationship between protein production and key cell-cycle checkpoint

Revealing a new way that cancer can evade immunotherapy — and, maybe, how to stop it
How a new technology solved a mystery and honors one man’s legacy

Immunotherapy has long-term benefit for patients with advanced Merkel cell carcinoma
‘Incredibly big change’ in treatment of deadly skin cancer, new data show

For cancer patients with HIV, immunotherapy appears safe
Checkpoint inhibitor study suggests new treatment options for patients long excluded from cancer immunotherapy clinical trials

The tumor microenvironment: How cancer fools healthy neighboring cells
‘Tumor microenvironment’ research underscores why we need cancer immunotherapy — and how to make it work for more patients

Forum at Fred Hutch focuses on the hottest developments in cancer immunotherapy
Immune-based treatments move from the fringes to the spotlight

Triple therapy for rare skin cancer shows promise in small, early-stage trial
Combo of T-cell therapy, newly FDA-approved drug and another immune booster kept cancer at bay for three of four patients with metastatic Merkel cell carcinoma