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Polygenic risk scores and prostate cancer
New research shows genetic risk scores could help distinguish who can cut back on ‘active surveillance’

Menopausal hormone therapy may lower the risk of colorectal cancer
From the Peters and Hsu Groups, Cancer Consortium & Public Health Sciences Division

A quarter century of lifesaving discoveries in prostate cancer
Pacific Northwest Prostate Cancer SPORE insights have transformed patient care and understanding of prostate cancer biology, supported drug discovery worldwide

BRCA1/2: Why men should be screened for the “breast cancer gene”
New research shows that men can carry mutations in the BRCA1 and BRCA2 genes that increase their risk of several cancers, but new national guidelines are helping to educate patients

Year in Pictures: 2022
A look back at the year through compelling images

Democratizing DNA-based health risk scores
Hutch-led consortium receives $9.8M grant to improve genetic risk prediction for cardiovascular disease in racially and ethnically diverse populations

Genetic similarities among some types of cancer
From the Lindstroem Group, Public Health Sciences Division

Removing barriers to precision treatment of metastatic prostate cancer
GENTleMEN study aims to help men with advanced disease access genetic testing and counseling

Common genetic disorder linked to increased death rate from cancer drug
Researchers recommend ‘caution’ when using the chemotherapy busulfan in patients with Gilbert’s syndrome

Progress in ‘precision prevention’ for colorectal cancer
New risk prediction model — not yet ready for clinical use — incorporates genetic, lifestyle and environmental risk factors

More than the 'Angelina Jolie Effect': BRCA testing spikes among breast cancer patients
Search for gene mutations began rising before actress revealed surgeries; better insurance coverage, access cited by experts

Testing without context
Nearly two-thirds of women who get tested for BRCA mutations don’t receive genetic counseling first

False positives in prenatal tests: Study reveals reason for flaws
Harmless variations in mothers’ DNA can trigger false positives in screen for chromosomal defects; study points to immediate fix test manufacturers can make

Family history of prostate cancer raises a woman's risk of breast cancer
Women’s Health Initiative study finds strongest association among African-American women

Hutchinson Center researcher secures $7.9 million NCI grant for esophageal cancer research
Study to evaluate genetic risk for Barrett’s esophagus and esophageal adenocarcinoma