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Gene specific alternative polyadenylation can reduce tumor growth
From the Bradley Lab, Basic and Public Health Sciences Divisions
Actively inactive: the regulation of RNA during quiescence in yeast cells
From the Tsukiyama Lab, Basic Sciences Division
To Ψ or not to Ψ: how PUS1 knows where to pseudouridylate mRNAs
From the Stoddard lab, Basic Sciences Division
Teaming up to understand mysterious microproteins
Dr. Arvind Subramaniam with multi-institutional team receives NIH Transformative Research Award to explore forces shaping microprotein evolution, potential roles in immunity and autoimmunity
RNA stability may play a role in prostate cancer
New research links mutations in RNA region that helps regulate protein production to progression and drug resistance
Circling back to RNA sequencing data to map recursive splice sites
From the Robert Bradley Lab, Public Health Sciences and Basic Sciences Divisions & Cancer Consortium
Cbf1 hace las veces de policía de tránsito transcripcional para equilibrar la función del centrómero
Del laboratorio Biggins, División de Ciencias Básicas
New therapeutic strategy turns a cancer’s advantage into its downfall
In the lab, researchers use synthetic mRNA to trick tumors into manufacturing cancer-specific poison
Dr. Steven Hahn elected to American Academy of Microbiology
Revealed fundamental properties of molecular machinery that creates mRNA
IAVI and Moderna launch trial of HIV vaccine antigens delivered through mRNA technology
Phase 1 trial aims to build on response seen in proof-of-concept trial
Hopes and predictions for 2022
Hutch researchers look ahead to an increase in cancer screening, improved vaccines and greater trust in science
Dr. Robert Bradley named scientific director of Fred Hutch Translational Data Science Integrated Research Center
Computational biologist will lead efforts to integrate data science in bench-to-bedside cancer research
Overlooked stretches of DNA could hide cancer-causing mutations
New cutting-edge technique sheds light on difficult-to-study DNA regions, potential drug targets
How RNA-altering drugs might improve anticancer immunotherapies
In lab study, brief disruptions of gene machinery make tumor cells more 'visible' to immune system
Dr. Rob Bradley named new McIlwain Family Endowed Chair in Data Science
Computational biologist uses data science to understand cancer biology and to seek new treatment targets
A cheaper way to study the immune system, one cell at a time
Scientists describe a more efficient way to sequence individual cells and visualize the massive amount of data that ensues
New research uncovers how common genetic mutation drives cancer
Findings in Nature show that targeted therapy for mutated gene can slow or prevent tumor growth in many kinds of cancer
‘Let the cells tell the story’
New tech is giving scientists unprecedented insights into single cells’ inner workings
10 highlights of Fred Hutch science in 2017
A look back at notable discoveries in cancer immunotherapy, HIV prevention and more
Study sheds new light on molecular pathways behind marrow disorders
How a single alteration in fundamental cellular machinery drives blood diseases and cancers