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New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
April 16, 2025

Now you see them, now you don’t: Gene editing protects stem cells from CAR T therapy
From the Kiem lab, Translational Science and Therapeutics Division

Uncovering a player responsible for boosting RIT1 protein abundance and cancer promoting activity
From the Berger Lab, Human Biology Division

Jennifer Doudna: ‘Curiosity-driven, fundamental science’ underpins Nobel Prize-winning work
CRISPR pioneer spoke at inaugural Fred Hutch President’s Seminar, outlined goals for gene-editing technology

Finding the golden ticket? Cyclin T1 is required for HIV-1 latency reactivation
From the Emerman lab, Human Biology and Basic Sciences Divisions

From the bench to Hutch services: Refining gene-editing methods for HSPCs used in pre-clinical applications
From the Paddison lab, Human Biology Division

Hitting ‘undo’ to cure Sickle Cell Disease
From the Lieber and Kiem Labs, Hematologic Malignancies Program, Cancer Consortium.

Panning for gold in a dependent-sea of genes
From the Emerman Lab, Human Biology and Basic Sciences Divisions

Uncovering cancer growth genes that have each other’s back when the other is down
From the Berger Lab, Human Biology Division

Searching beyond the streetlight to uncover functional protein domains
From the Paddison Lab, Human Biology Division

Could gene twins team up against cancer?
New approach uncovers gene duplications that could be targets for cancer drugs

TOP delivery of CRISPR-Cas9 machinery to primary T cells
From the Overbaugh Lab, Human Biology Division

Advances in blood disorders research continue despite COVID-19
Expanding use of CAR T-cell therapies, gene editing lead to insights at virtual annual meeting of the American Society of Hematology

Improved CRISPR-Cas9 delivery method allows for fast and precise knockouts
From the Paddison lab, Human Biology Division

¿La cura del herpes? Hay avances que reportar
Los estudios con ratones muestran que la terapia génica puede reducir muchísimo las infecciones inactivas

Discovering new strategies used in arms race between bacteria and the viruses that infect them
Dr. Kevin Forsberg tapped for NIAID New Innovators Award to study arms race between viruses and bacteria

Your vote needed! Hutch science competes in 'STAT Madness'
Studies by Drs. Justin Taylor, Robert Bradley are finalists in annual competition for best biomedical advance

Catching CRISPR/Cas9 in (Pig Farm)
From the Bradley lab, Basic Sciences and Public Health Sciences Divisions

Gimme shelter: CRISPR hides healthy cells from leukemia drug
In mouse study, gene-edited cells stay safe as immunotherapy attacks cancer

How a common cancer mutation actually drives cancer — and how to correct it
High-tech approach solves ‘real mystery’ in many cancers