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Cell free DNA profiling may unlock the key to studying small cell lung cancer
MacPherson and Ha Labs in the Division of Human Biology

Targeted new approach and computational tools reveal lung cancer subtypes hiding in patterns in cell-free DNA
Innovative strategy a step toward liquid biopsy to detect, monitor aggressive small cell lung cancer

When antibodies become anti-body
From the Houghton and Lampe labs, Clinical Research and Public Health Sciences Divisions

MacPherson Lab puts immunologically cold cancers in the hot seat with combination therapy
From the MacPherson and Srivastava Labs, Cancer Basic Biology and Cancer Immunology Programs, Cancer Consortium.

CD133 auto-antibodies shine a light on early-stage small cell lung cancer
From the Dr. Paul D Lampe, Dr. Christopher Li, and Dr. A McGarry Houghton Labs, Cancer Epidemiology, Prevention and Control and Cancer Immunology Programs, Cancer Consortium.

Making immunotherapy more effective against small cell lung cancer
Human trial opens after experimental drug improves tumor growth suppression in mice

Tip Sheet: Colorectal cancer, COVID-19 super-spreading, gene therapy for herpes, contagious cancer in Tasmanian devils – and more
Summaries of recent Fred Hutch research findings and other news with links for additional background and media contacts.

New insights into drug resistance in small cell lung cancer
Scientists discover a single gene’s outsized role in drug resistance — and use its vulnerability to re-sensitize tumors to chemotherapy in preclinical models

In cancer, the context 'makes' the mutation
Whether a mutated gene suppresses or promotes small-cell lung cancer depends on other mutations

Q&A: A new focus on small cell lung cancer
Dr. David MacPherson discusses the state of small cell lung cancer research, how his lab is tackling this deadly disease, and what makes him excited for the future

Path to a targeted treatment for small-cell lung cancer?
Researchers show how common mutation in SCLC makes mouse tumors more vulnerable to certain cancer drugs

Good News: Fred Hutch joins coalition that seeks to increase transparency on life science career prospects
Celebrating faculty and staff achievements