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Rewriting the story about the molecules that turn genes on and off
Fred Hutch researchers discover that most transcription factors in budding yeast don’t follow the textbook example of binding close to the genes they regulate
New Science Spotlight Articles
Every month, Fred Hutch postdoc writer/editors summarize two papers from each of our scientific divisions to stimulate collaborations across campus
April 16, 2025

Cell biologist and former Fred Hutch division leader Dr. Jonathan Cooper retires
Cooper sustained the distinct culture of Basic Sciences for four decades

Drs. Keith Jerome and Jesse Bloom elected fellows of American Academy of Microbiology
Fred Hutch researchers’ study of viruses evolves from basic understanding to practical applications

New methods reveal cancer mechanism in ancient genes
Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies

Evolutionary cell biologist Dr. Grant King named a Hanna Gray Fellow
Long fascinated by life seen and unseen, King awarded eight years of funding to finish postdoctoral training at Fred Hutch and establish an independent lab

Cold air makes oxygen toxic for worms
Fred Hutch study shows C. elegans, a microscopic worm, can survive low temperatures if oxygen supply is also low

Tricking cells into trashing cancer
Fred Hutch chemical biologist rapidly reduces lung tumors in mice with a tagging system that grabs cancer-causing proteins and hauls them out with the molecular trash

50 years of doing hard things
Founded in 1975 to honor a brother, Fred Hutch Cancer Center pursued bold science, pioneered a cure for blood diseases that changed medicine and became a world-class biomedical research and clinical care institution

Sharing AI insights without sharing patient data
Fred Hutch Q&A about leading alliance to leverage power of artificial intelligence responsibly in research and care

Blocking a cancer escape hatch
Fred Hutch graduate student wins NIH F31 award to study structure of a key protein that helps blood vessels grow, but also helps cancer spread when it malfunctions

Cracking the sparkle code
Fred Hutch cancer biologist wins V Foundation Scholar Award to explore role of protein sugaring in leukemia tumors that survive chemotherapy

New deputy CMO brings Texas-sized expertise to Fred Hutch
Dr. Nicole Fleming takes over daily operations of South Lake Union clinic that has grown by 30% in three years

Finding a new way to break the supply chain fueling advanced prostate cancer
Fred Hutch researcher wins a $1M grant for a London-Seattle collaboration to find new therapies for drug-resistant prostate cancer

Finding passion and community
Fred Hutch Postbaccalaureate Scholar Program bridges gap between college and graduate school for aspiring scientists

Bottleneck breakthrough
Fred Hutch researchers discover why some HIV-1 variants are more transmissible than others, which could generate new approaches to stop the virus that causes AIDS at cell entry

Making the most of a small supply
Fred Hutch researchers receive $1.3 million grant from the U.S. Department of Defense to study the fundamental biology of five rare liver cancers that could lead to new treatments one day

Almost as good as delivering flowers
Volunteer driver Bill Conquergood fights traffic so out-of-state patients don’t have to

Priming the pump for future funding
Fred Hutch postdoctoral researchers win NIH training fellowship for pancreatic cancer and kinetochore projects

Cell biologist Dr. Susan Parkhurst named 2024 ASCB fellow
Fred Hutch researcher honored by American Society for Cell Biology discusses integrating generations of scientists through mentorship

Making the leap from postdoc to principal investigator
Fred Hutch postdoctoral research fellow hopes to run her own lab with a transition award from the Cystic Fibrosis Foundation