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Novel regimen greatly reduced chronic GVHD in phase 2 study at Fred Hutch
Substituting cyclophosphamide for a standard post-transplant immunosuppressant is a “gamechanger”

Could fecal microbiota transplantation help patients heal after stem cell transplantation?
Phase 2 clinical trial shows a safe dose from a specific donor helped with gut microbiome recovery in people with cancer

Graft-versus-host disease outcomes improving for all Fred Hutch patients
From the Long-Term Follow-Up Research Group, Clinical Research Division

Secret to tamping down GVHD may lie in microbial genetics
Preclinical bone marrow transplant study shows donor immune cells that target recipient microbiome can influence GVHD severity

All eyes on IL-6 when it comes to CMV reactivation after bone marrow transplantation
From the Hill Lab in Translational Sciences and Therapuetics Division

Aplastic anemia diagnosis took business strategy manager by surprise
Transplant replaced his failing bone marrow with healthy cells

Caregivers know compassion is critical; staying organized is, too
One woman shares tips on caring for a spouse going through blood cancer treatment

Pre-transplant microbiome sets the stage for GVHD
Preclinical findings highlight bacterial groups that influence GVHD risk

New approach could make bone marrow transplantation safer, stronger
Tests prevented relapse, limited GVHD in laboratory models of leukemia, multiple myeloma

Dispatches from the microbial frontier of cancer research
Hutch scientists aim high by way of the lowly microorganisms that call us home

Commensals turn pathogenic in graft-vs-host disease
From the University of Michigan and the Fredricks Lab, Vaccine and Infectious Disease Division

Mystery solved: How graft-vs.-host disease starts in the gut
Microbiome triggers top killer after bone marrow transplant — and there’s a potential way to stop it

How a phone call helped shape the field of bone marrow transplant
A lifesaving new leukemia treatment was harming some patients’ digestive organs, and no one really understood why. So, over 40 years, Dr. George McDonald helped fill in the gaps.

Dr. Stephanie Lee honored as new Giuliani/Press Endowed Chair recipient
The honor will support Lee in perpetuity as she continues her research on blood stem cell transplantation and chronic GVHD

Fred Hutch deepens its focus on the microbiome
Microbiome Research Initiative hosts 2-day symposium

Washington’s Andy Hill Cancer Research Endowment awards $1.5M to 3 Fred Hutch researchers
Scientists will use funds to expand research in graft-vs.-host disease, chemoprevention and cancer immunology

Dr. Marie Bleakley named Gerdin Family Endowed Chair for Leukemia Research
Pediatric cancer physician-scientist feted at rooftop reception